Abbreviations

  • β2GP1 - β2 glycoprotein 1
  • 11-DOH - 11-dehydrothromboxane B2
  • AACC - American Association for Clinical Chemistry
  • ACA - anti-cardiolipin antibody (also ACL)
  • ACL - Anti-cardiolipin antibody (also ACA)
  • ACT - activated clotting time assay
  • ADAMTS - A disintegrin-like and metalloprotease domain with thrombospondin motifs (also VWF-cleaving protease)
  • ADP - Adenosine diphosphate
  • AF - atrial fibrillation
  • AFIB - Atrial fibrillation
  • AMI - Acute myocardial infarction
  • anti-Xa - chromogenic anti-Xa anticoagulant assay
  • APC - Activated protein C
  • APCR - Activated protein C resistance
  • APL - Anti-phospholipid antibody
  • APTT - activated partial thromboplastin time, partial thromboplastin time
  • ARU - aspirin resistance unit
  • ASA - Aspirin; acetyl salicylic acid
  • ASCLS - American Society for Clinical Laboratory Science
  • AT - antithrombin or antithrombin III
  • ATIII - antithrombin III or antithrombin
  • ATP - Adenosine triphosphate
  • BMJ - British Medical Journal
  • BSS - Bernard-Soulier syndrome
  • BT - Bleeding time
  • BU - Bethesda units
  • CABG - Coronary artery bypass graft
  • CAPS - Catastrophic antiphospholipid syndrome
  • CBC - complete blood count
  • CDC - US Centers for Disease Control and Prevention
  • CLIA - Clinical Laboratory Improvement Amendments
  • CLIAC - Clinical Laboratory Improvement Advisory Committee
  • CLL - chronic lymphocytic leukemia
  • COX - cyclooxygenase
  • COX-1 - cyclooxygenase-1
  • COX-2 - cyclooxygenase-2
  • CVA - Cerebrovascular accident
  • D-D - D-dimer
  • DAPT - dual anti-platelet therapy
  • DDAVP - Desamino-8-D-arginine vasopressin, desmopressin
  • DIC - Disseminated intravascular coagulation
  • DOAC - Direct oral anticoagulant (also TSOAC and NOAC)
  • DRVVT - Dilute Russell viper venom time
  • DTI - Direct thrombin inhibitor
  • DTS - Dense tubular system
  • DVT - Deep venous thrombosis
  • EC - Endothelial cell
  • ECA - Stago's Ecarin Chromogenic Assay
  • ECMO - Extra-corporeal membrane oxygenation
  • ECT - Ecarin clotting time
  • ED - emergency department, emergency room
  • EIA - Enzyme immunoassay
  • ELISA - Enzyme-linked immunosorbent assay
  • ELT - Euglobulin lysis time
  • ER - emergency room, emergency department
  • ESRD - end stage renal disease
  • FB - Fibroblast
  • FDA - US Food and Drug Administration
  • FDP - Fibrin (ogen) degradation products
  • FEIBA - Factor VIII inhibitor bypassing activity
  • FFP - Fresh frozen plasma
  • Fg - Fibrinogen
  • FP24 - 24-hour frozen plasma
  • FSP - Fibrin (ogen) split products
  • FVIII - Factor VIII
  • FVIII:C - Factor VIII coagulant activity
  • FVIIIR:Ag - Factor VIII related antigen (VWF-related antigen)
  • FVL - Factor V Leiden mutation
  • g/dL - grams per deciliter
  • GP Ib - Glycoprotein Ib
  • GP IIb - Glycoprotein IIb
  • GP IIb/IIIa - Glycoprotein IIb/IIIa
  • GP IX - Glycoprotein IX
  • GP V - Glycoprotein V
  • GT - Glanzmann thrombasthenia
  • Hb - hemoglobin, HGB
  • HCT - hematocrit
  • HCY - Homocysteine
  • HGB - hemoglobin, Hb
  • HIT - Heparin-induced thrombocytopenia with thrombosis
  • HITT - Heparin-induced thrombocytopenia with thrombosis
  • HMWK - High molecular weight kininogen (Fitzgerald factor)
  • HPA - Human platelet antigen
  • HRT - Hormone replacement therapy
  • ICH - Intracranial hemorrhage
  • IL - Interleukin
  • IM - Intramuscular
  • INR - International normalized ratio
  • IRP - International reference preparation
  • ISI - International sensitivity index
  • ISTH - International Society on Thrombosis and Haemostasis
  • ITP - Immune thrombocytopenic purpura
  • IV - Intravascular
  • IVIg - Intravenous immunoglobulin
  • JACC - Journal of the American College of Cardiology
  • LA - lupus anticoagulant
  • LAC - Lupus anticoagulant
  • LDT - lab-developed test
  • LIA - Latex immunoassay
  • LMWH - Low molecular weight heparin
  • LVAD - Left ventricular assist device
  • mg/dL - milligrams per deciliter
  • MNPT - Mean normal prothrombin time
  • MPD - Myeloproliferative disorder
  • MRI - mean of the reference interval
  • NATP - Neonatal alloimmune thrombocytopenic purpura
  • ng/mL - nanograms per milliliter
  • NO - nitric oxide
  • NOAC - Novel oral anticoagulant (or non-VK oral anticoagulant, also DOAC or TSOAC)
  • NP - Normal plasma
  • NSAIDS - Non-steroidal anti-inflammatory drugs
  • NVAF - non-valvular atrial fibrillation
  • OC - Oral contraceptive
  • OCR - Oral contraceptive
  • OCS - Open canalicular system
  • PAD - peripheral artery disease, peripheral artery occlusion
  • PAI-1 - plasminogen activator inhibitor-1
  • PAO - peripheral artery occlusion, peripheral artery disease
  • PC - Protein C
  • PCC - Prothrombin complex concentrate
  • PCI - Percutaneous coronary intervention
  • PCR - polymerase chain reaction
  • PE - Pulmonary embolism
  • PECAM - Platelet-endothelial cell adhesion molecule
  • PF 1+2 - Prothrombin fragment 1+2
  • PF 1.2 - Prothrombin fragment 1.2
  • PF4 - Platelet factor 4
  • PFA - Platelet function analyzer
  • PFP - Platelet-free plasma
  • PG - Prostaglandin
  • PIVKA - Proteins in vitamin K antagonism
  • PK - Prekallikrein (Fletcher factor)
  • PL - phospholipid
  • PLA - Human platelet antigen
  • PLC - Phospholipase C
  • PLT - platelet
  • PNP - Pooled normal plasma
  • POC - point of care
  • PPP - Platelet-poor plasma
  • PRP - Platelet-rich plasma
  • PS - Protein S
  • PT - prothrombin time (protime)
  • PT/INR - Prothrombin time with international normalized ratio
  • PTR - Prothrombin time ratio
  • PTs - Prothrombin time (protime)
  • PTT - partial thromboplastin time, activated partial thromboplastin time
  • PTTs - Activated partial thromboplastin time
  • RBC - Red blood cell
  • RI - reference interval, "normal range"
  • RIPA - ristocetin-induced platelet aggregation
  • RNA - ribonucleic acid
  • ROC - receiver-operating characteristic
  • ROTEM - rotational thromboelastometry
  • RVVT - Russell viper venom time
  • SAK - Staphylokinase
  • SC - Subcutaneous
  • SERPIN - Serine protease inhibitor
  • SK - Streptokinase
  • SMC - Smooth muscle cell
  • SPRCA - Solid-phase red blood cell agglutination assay
  • SQ - Subcutaneous
  • TAFI - Thrombin activated fibrinolysis inhibitor
  • TAT - Thrombin-antithrombin
  • TCT - Thrombin clotting time
  • TEG - thromboelastograph, thromboelastography
  • TEM - Rotational thromboelastometry
  • TF - Tissue factor
  • TIA - Transient ischemic attack
  • TM - Thrombomodulin
  • TNF - Tumor necrosis factor
  • TPA - Tissue plasminogen activator
  • TSOAC - Target-specific oral anticoagulant (also NOAC or DOAC)
  • TT - Thrombin clotting time
  • TTI - Tissue thromboplastin inhibition
  • TTP - Thrombotic thrombocytopenic purpura
  • TTR - Time in therapeutic range
  • TXA2 - Thromboxane A2
  • TXB2 - Thromboxane B2
  • UA - Unstable angina
  • UFH - Unfractionated (standard) heparin
  • UK - Urokinase
  • UK - Urokinase
  • VK - Vitamin K
  • VKA - Vitamin K antagonist
  • VTE - Venous thromboembolism
  • VWD - von Willebrand disease
  • VWF - von Willebrand factor
  • VWF:Ac - von Willebrand factor activity
  • VWF:Ag - von Willebrand factor antigen
  • VWF:CBA - von Willebrand factor collagen binding activity
  • VWF:RCo - von Willebrand factor ristocetin cofactor activity
  • WBC - White blood cell
  • YO - year-old, years of age