Thrombotic Thrombocytopenic Purpura

Click “In Their Blood” for a review article about TTP from the University of Kansas (KU) Medical Center’s Pathology Department. The article highlights the early research into ADAMTS13‘s role in VWF metabolism, the early successes of PLEX therapy, and the current availability of the therapeutics caplacizumab and the ADAMTS13 concentrate, Adzynma. Also featured is the current KU development of an ADAMTS13 assay that is available to acute care facilities.
The article cites Long Zheng, M.D., Ph.D., Russell J. Eilers Endowed Professor and chair of the Department of Pathology and Laboratory Medicine, who offered a January 10, 2021 “Coag Conversations” webinar, “von Willebrand Factor–Friend or Foe.”