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What is PITT?

Jun 2 2025
George Fritsma
Click below for an open-access article that classifies VITT and HIT as members of a platelet factor 4 (PF4) disorder, anti-PF4 mediated thrombocytopenia and thrombosis (PITT).
Nicolson PLR, Montague SJ, Buka RJ, et al. Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics. Br J Haematol. 2025. doi: 10.1111/bjh.20092. Epub ahead of print. PMID: 40298004.
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George Fritsma MS MLS

George Fritsma is a medical laboratory scientist, educator, and author. George holds faculty appointments with Rutgers University and Michigan State University, and is a member of the International Society on Thrombosis and Hemostasis, American Association of Clinical Chemists, and American Society for Clinical Laboratory Science.

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Which fibrinolysis component directly digests fibrin?