Announcing a 9-30-20 open access publication [forgive the self-reference]: McGlasson DL, Fritsma, GA. In vitro detection and removal of direct oral anticoagulants from patient plasma specimens. Annals of Blood 2020:doi: 10.21037/aob-20-16.
Posts - Specimen Management
Oct 15, 2020 1:09pm
Sep 2, 2020 8:46am
Hi, I used to work in special coag at VCU, it was over 10 years ago. When we were freezing specimens we had to double spin them at 3500 rpm for 15 minutes. Our quick-spin centrifuges for PT/PTT could cause the platelets to leak out their activation factors. Where I now work, we called Mayo and UVA who claim to have never heard of this. I only process for send outs occasionally but when I do I cannot bring myself to use the quick centrifuges since I was trained differently, however, if this is an outdated practice, I can change but I don't want to do so without verification from someone I trust. Thank you, Anne.
Aug 15, 2020 1:27pm
George received a comment about platelet-poor plasma [PPP ] from friend and colleague, Heather DeVries, Indiana University Health. Here is a paragraph from Fritsma GA. Laboratory evaluation of hemostasis, Chapter 41 in Keohane EM, Otto CN, Walenga JM. Rodak's Hematology: Clinical Principles and Applications, 6th Edition, Elsevier, 2020. ISBN 978-0-323-53045-3: