I [Geo] will present "Hemostasis in the Operating Room" at the American Society for Clinical Laboratory Sciences Joint Annual Meeting in Grand Rapids, Michigan, Wednesday, tomorrow, June 29, 1:45–2:45 EDT.
Posts - Instrumentation
Jun 10, 2022 12:18pm
Oct 23, 2020 12:44pm
Mike Meyer asks, "we run three dilutions for all of our factor testing. Occasionally, we see results in which upon higher dilutions, the factor value decreases after adjusting for the dilution. For instance, I had a case today in which the FIX values were 0.64, 0.55, and 0.43 U/mL for the 1:10, 1:20, and 1:40 dilutions [values corrected for the dilution effect], the opposite effect seen with inhibitors. Calibration curve seems fine." He adds, "the patient’s FVIII level was very high [about 3.60 U/mL]. We possibly thought that the higher dilutions would bring the FVIII level back closer to a more normal range. The high concentration of FVIII in the first dilution may be accelerating the PTT clotting time yielding a falsely higher FIX value. Please comment."
Nov 10, 2018 6:26am
Thanks to Ali Sadeghi-Khomami PhD, Precision BioLogic, and Joan Polancic, MS MLS, Denver Health, for the heads-up on this announcemment: