Posts - Global Hemostasis Assays

Sep 18, 2020 7:38pm
From Deanna Miller, Children's Hospital of Alabama. Do you have any good references for diluted thrombin and utilization of this test?  What dilution is best? 1:1 or 1:3?
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Aug 26, 2020 6:26pm
You are invited to our Tuesday, September 15, 2020 webinar, Covid-Associated Coagulopathy: A Conversation about the Controversies and Confusion featuring pathology expert Andrew J. Goodwin, MD, University of Vermont Medical Center Laboratory Director.
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Jan 22, 2018 10:41am
From Alan Neal, Pathlab, NZ. Just wanted a private conversation about the January 11, 2018 Fritsma Factor entry, "POC and Plasma-Based PT/INRs." I do not agree with the comments made within this article and challenge the logic used. Essentially, if monitoring an enzymatic pathway such as coagulation, with the 'detector' being used is fibrinogen to fibrin, then that rate of reaction will be dependent on the substrate concentration, i. e., fibrinogen, and the sensitivity of the analyser to detect the end point. So if no or reduced fibrinogen or dysfibrinogen, then reduced Vmax and hence PT/INR will be more prolonged than test system using a clot based end point detection.
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Aug 17, 2017 9:20am
Odetta Hanna from Sekisui Diagnostics asked, "Do you have a good resource to obtain the medical decision points for coagulation assays?"
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