Posts - Fibrinolysis

Jan 19, 2020 6:17pm
Click or tap here for a January, 2020 Karen Titus CAP Today feature article on concerns around D-dimer assay reporting.
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Sep 27, 2019 12:42pm
A colleague has seen references to a "High-sensitivity" D-dimer assay. George answered he's not heard of this, perhaps it is just a synonym for a standard D-dimer assay. If you have any experience with this, please respond to george@fritsmafactor.com or comment below.  
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Sep 27, 2019 9:55am
From Heather DeVries, Indiana University Medical Center. I’m seeking some advice on how to handle D-dimers in patients with elevated hematocrits. I saw a post on this subject in Fritsma Factor back in 2013. CLSI H59-A says to follow H21-A5 in general, which of course says to correct the anticoagulant volume. IL ’s package insert for D-dimers also says to follow H21-A5. So, I revised the D-dimer procedure for our system to include adjusted tubes. Now I am being asked by one of our sites if that is really necessary. My mind goes to a possible dilutional effect, which is what the post from 2013 mentions as well. But I didn’t see any follow up and am curious to know which direction the conversation took.
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